Air Buster: Trouble Specialty Raid Unit a.k.a. Aero Blasters: Trouble Specialty Raid Unit is a 1990 horizontally scrolling shoot 'em up video game developed and published by Kaneko and licensed to Namco. The game was originally released in the arcades in 1990 and was subsequently released for the PC Engine/TurboGrafx-16 (as Aero Blasters) and Sega Mega Drive/Genesis (as Air Buster in North America) in 1990 and 1991 respectively.In Air Buster, the player controls a fighter jet also designed for space travel and shoots enemies, collects power-ups, and defeats bosses to advance levels. As a console game, Air Buster had the distinction of being two player simultaneous, which was rare among side scrolling shooters on home consoles at the time; all games in the Thunder Force, Gradius, and R-Type series were only 1 player on the home consoles.

Air Diver: F-119 Stealth Fighter Simulation (エアダイバー?) is a combat flight simulator video game released by Seismic (Asmik Ace Entertainment in Japan) in April 1990 for the Sega Genesis/Mega Drive console. It is notable as being one of the two first third party published titles for the console in North America. A follow-up, Super Air Diver was released exclusively for the Super Nintendo Entertainment System years later.

Castlevania: Bloodlines is a platform game developed and published by Konami for the Sega Genesis (Mega Drive) in 1994. It is the only Castlevania video game released on the Mega Drive/Genesis. Its Japanese title is Vampire Killer (バンパイアキラー Banpaia Kirā?). This version featured a considerable amount of violence, with the American port containing a surprising amount of blood and gore for a game of its "GA" rating. The European and Australian titles were censored and both titled Castlevania: The New Generation.

Disney's Aladdin is a series of platformer video games based on the 1992 motion picture of the same name. The series consists of three drastically different games: one developed by Virgin Interactive for the Sega Mega Drive, which was ported to various other formats, another developed by Capcom for the Super Nintendo Entertainment System, which was later ported to the Game Boy Advance, and a final version developed by SIMS for the Sega Master System and Game Gear.

Aladdin II is an unlicensed Mega Drive port of the SNES version of Disney's Aladdin, originally made by Capcom in 1994. It might has been developed by ex-workers from Chuanpu Technology and was likely published by X Boy. This port can be considered the "opposite" of Aladdin 2000, a port of Virgin's Aladdin to the SNES.

Aleste (アレスタ?) is a 1988 shoot 'em up video game developed by Compile for the Master System. It is a direct successor to Compile's earlier Zanac, featuring many of the themes and gameplay mechanics of that work.

Alex Kidd in the Enchanted Castle (アレックスキッド 天空魔城, Arekkusu Kiddo Tenkū Majō?) is a side-scrolling platform game developed and published by Sega for the Sega Genesis video game console. The game was released in Japan in February 1989, in the U.S. in January 1990 and in Europe on November 1990. It is the only 16-bit platform game starring Alex Kidd, and the fifth game in the Alex Kidd series of video games. Alex Kidd in the Enchanted Castle follows Alex as he fights his way through the fictional planet Paperock in search of his long-lost father, King Thor. Alex has access to several items and vehicles that help him complete his quest, including a motorbike, pedicopter, and pogo stick, which each give him unique abilities. While traveling through eleven worlds, Alex must defeat several opponents in rock-paper-scissors before finally finding King Thor.

Alien3 is a 1992 video game published by Arena Entertainment, Acclaim Entertainment, LJN, Virgin Interactive and Tectoy for the Amiga, Commodore 64, and Sega Master System. It is based on the film of the same name. The game was also released for the Nintendo Entertainment System and Sega Genesis in 1993 and the Sega Game Gear in 1994.

Alien Soldier (エイリアンソルジャー?) is a side-scrolling run and gun video game developed by Treasure for the Sega Mega Drive. The game was released in Japan and Europe, but not physically in the US (one of the few to be released in this pattern), but it can be rather expensive due to its rarity in either region. The game was playable in America on the Sega Channel cable service and has been reissued for PlayStation 2 as part of the Sega Ages Treasure Box disc. The Sega Ages version, whose disc also includes Treasure's Gunstar Heroes and Dynamite Headdy, exceeds the Mega Drive's intrinsic sprite display limit, which eliminates slowdowns or missing graphics during busy scenes (e.g. boss fights with many explosions). Also, the player can select either the sprite-based pixelated graphics of the original game or a new mode that uses certain filters to produce a high-resolution look. The game was re-released again on the Nintendo Wii's Virtual Console download service in Japan on October 9, 2007, in Europe on November 2, 2007, and North America debut on November 5, 2007. The game is listed in Guinness World Records Gamers Edition 2010 under the category "Most boss battles in a run and gun game". The catchphrases seen on the title screen, "FOR MEGADRIVERS CUSTOM" and "VISUALSHOCK! SPEEDSHOCK! SOUNDSHOCK! NOW IS TIME TO THE 68000 HEART ON FIRE!", describe the game's technical prowess for the Mega Drive hardware, at the core of which is the Motorola 68000 CPU.

Alien Storm (エイリアンストーム?) is a 1990 beat 'em up arcade game by Sega. It was later ported to the Sega Mega Drive/Genesis and Sega Master System. The Sega Mega Drive version was also released on Wii's Virtual Console in 2007. The game appeared in Sega Mega Drive Ultimate Collection for Xbox 360 and PlayStation 3.

Alisia Dragoon (アリシア ドラグーン) is a 1992 platform game for the Sega Mega Drive/Genesis. It was developed by Game Arts, who also published the game in Japan. Aiding the software developer was animation studio Gainax, who was responsible for the game's art and story. The player controls Alisia, a young woman who is on a quest to avenge her father and save the world. She can fire lightning from her hands and summon four faithful beasts to aid her. The game was released in North America and Europe by Sega, who packaged the heroine as a rugged gladiator instead of the dainty-looking sorceress she originally was. Due to the lack of substantial market penetration by the Mega Drive of Japan and the lack of publicity for the game overseas, Alisia Dragoon did not make a big impact on the video game market, despite the critical acclaim it received. The game was one of the first in the industry to present a female character in a leading role.

Altered Beast (獣王記, Jūōki?, lit. "Beast King's Chronicle") is a 1988 beat 'em up arcade game developed and manufactured by Sega. The game is set in Ancient Greece, and follows a centurion who is resurrected by Zeus to rescue his daughter Athena, and to do so becomes able to turn into beasts such as the werewolf with the use of power-ups. After its initial arcade release, it was ported to several home video game consoles and home computers, including the Sega Mega Drive and Sega Genesis, for which it was a pack-in game. This ultimately led to the Sega Genesis being shipped with Sonic the Hedgehog instead. The primary designer was Makoto Uchida, also responsible for the creation of Golden Axe.