Zero Tolerance is a 1994 video game developed by Technopop and published by Accolade exclusively for the Sega Mega Drive/Genesis video game console. It was one of the few Mega Drive/Genesis first person shooters, besides Bloodshot and the Duke Nukem 3D port. Due to the limitations of the hardware, the player's view of the 3D environment was restricted to a fraction of the screen, with the player's HUD, a map of the surrounding area, and the player character's ID card comprising the rest of the screen space. Still, it featured impressive visual effects for its time and especially for the Genesis, a system with hardware that lacked much of the necessary scaling and rotation technologies normally needed to create even the most rudimentary appearance of 3D environments (such as rival Super NES' built-in "Mode 7" technology and "Super FX Chip" add-on). In fact, the smoothness and speed at which Zero Tolerance ran was said to rival many of the lower-end versions of Doom available at the time.

Zero Wing (ゼロウィング, Zero Uingu?) is a 1989 side-scrolling shoot 'em up arcade game developed by Toaplan and published by Taito. The player is a lone hero who will save the universe from an evil force. It enjoyed a degree of success in arcades and was subsequently ported to the Mega Drive by Toaplan on May 31, 1991, in Japan, and by Sega during the following year in Europe, followed by a Japan-only release by Naxat Soft on September 18, 1992, for the PC Engine's CD-ROM². The European version of the Mega Drive port was the source for "All your base are belong to us", an Internet meme which plays off of the poorly translated English in the game's introduction.