Aleste (アレスタ?) is a 1988 shoot 'em up video game developed by Compile for the Master System. It is a direct successor to Compile's earlier Zanac, featuring many of the themes and gameplay mechanics of that work.

Alex Kidd in the Enchanted Castle (アレックスキッド 天空魔城, Arekkusu Kiddo Tenkū Majō?) is a side-scrolling platform game developed and published by Sega for the Sega Genesis video game console. The game was released in Japan in February 1989, in the U.S. in January 1990 and in Europe on November 1990. It is the only 16-bit platform game starring Alex Kidd, and the fifth game in the Alex Kidd series of video games. Alex Kidd in the Enchanted Castle follows Alex as he fights his way through the fictional planet Paperock in search of his long-lost father, King Thor. Alex has access to several items and vehicles that help him complete his quest, including a motorbike, pedicopter, and pogo stick, which each give him unique abilities. While traveling through eleven worlds, Alex must defeat several opponents in rock-paper-scissors before finally finding King Thor.

Alien Soldier (エイリアンソルジャー?) is a side-scrolling run and gun video game developed by Treasure for the Sega Mega Drive. The game was released in Japan and Europe, but not physically in the US (one of the few to be released in this pattern), but it can be rather expensive due to its rarity in either region. The game was playable in America on the Sega Channel cable service and has been reissued for PlayStation 2 as part of the Sega Ages Treasure Box disc. The Sega Ages version, whose disc also includes Treasure's Gunstar Heroes and Dynamite Headdy, exceeds the Mega Drive's intrinsic sprite display limit, which eliminates slowdowns or missing graphics during busy scenes (e.g. boss fights with many explosions). Also, the player can select either the sprite-based pixelated graphics of the original game or a new mode that uses certain filters to produce a high-resolution look. The game was re-released again on the Nintendo Wii's Virtual Console download service in Japan on October 9, 2007, in Europe on November 2, 2007, and North America debut on November 5, 2007. The game is listed in Guinness World Records Gamers Edition 2010 under the category "Most boss battles in a run and gun game". The catchphrases seen on the title screen, "FOR MEGADRIVERS CUSTOM" and "VISUALSHOCK! SPEEDSHOCK! SOUNDSHOCK! NOW IS TIME TO THE 68000 HEART ON FIRE!", describe the game's technical prowess for the Mega Drive hardware, at the core of which is the Motorola 68000 CPU.

Alien Storm (エイリアンストーム?) is a 1990 beat 'em up arcade game by Sega. It was later ported to the Sega Mega Drive/Genesis and Sega Master System. The Sega Mega Drive version was also released on Wii's Virtual Console in 2007. The game appeared in Sega Mega Drive Ultimate Collection for Xbox 360 and PlayStation 3.

Altered Beast (獣王記, Jūōki?, lit. "Beast King's Chronicle") is a 1988 beat 'em up arcade game developed and manufactured by Sega. The game is set in Ancient Greece, and follows a centurion who is resurrected by Zeus to rescue his daughter Athena, and to do so becomes able to turn into beasts such as the werewolf with the use of power-ups. After its initial arcade release, it was ported to several home video game consoles and home computers, including the Sega Mega Drive and Sega Genesis, for which it was a pack-in game. This ultimately led to the Sega Genesis being shipped with Sonic the Hedgehog instead. The primary designer was Makoto Uchida, also responsible for the creation of Golden Axe.

American Gladiators is an American competition television program that aired weekly in syndication from September 1989 to May 1996. The series matched a cast of amateur athletes against each other, as well as against the show's own gladiators, in contests of strength and agility. The concept was created by Dan Carr and John C. Ferraro, who held the original competition at Erie Tech High School in Erie, Pennsylvania. They sold the show to The Samuel Goldwyn Company (later MGM) where the concept was enhanced and became American Gladiators. An effort in 2004 to launch a live American Gladiators show on the Las Vegas Strip became mired in a securities fraud prosecution. However, the television series was restarted in 2008. Episodes from the original series were played on ESPN Classic from 2007 to 2009. Several episodes are available for download on Apple's iTunes Service.

Arch Rivals is a basketball arcade game released by Midway in 1989. Billed by Midway as "A Basket Brawl", the game features two-on-two full court basketball games in which players are encouraged to punch opposing players and steal the ball from them. Arch Rivals allows players to select from a variety of fictional teams (although arcade operators can change the team names to reflect real ones) and players. One playable character, "Tyrone" was also featured in the animated Power Team segments of the television series Video Power. Home versions of the game were released for the Nintendo Entertainment System, the Sega Genesis/Mega Drive as well as the Game Gear. Emulated versions of the game were included in the compilations Midway Arcade Treasures 2, Midway Arcade Treasures Deluxe Edition, and Midway Arcade Origins. The game has been considered a forerunner to Midway's popular arcade basketball game, NBA Jam.

Ariel the Little Mermaid is a video game that was developed by Blue Sky software and released for the Sega Genesis in 1992.