Battletoads is a video game media franchise by Rare that began with the original beat 'em up game Battletoads in 1991. Starring three anthropomorphic toads named after skin conditions, Rash, Zitz, and Pimple, the series was created to rival the Teenage Mutant Ninja Turtles games. The series as a whole has been quite popular and at its apex spawned an animated television pilot. The initial Battletoads game for the NES was renowned for its difficulty, but was well received and spawned sequels for various platforms including a crossover with the Double Dragon series. In each of the games, the objective is to defeat the toads' nemesis the Dark Queen and her army of space mutants. Most titles in the series do not feature all three toads as playable characters, with one or two members of the team being captured by the Dark Queen. The exceptions to this were Battletoads & Double Dragon and the Battletoads arcade game.

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Bio-ship Paladin, known in Japan as Space Battleship Gomora (宇宙戦艦ゴモラ?), is a 1990 horizontally scrolling shoot 'em up arcade game. It was later ported to the Sega Mega Drive. While the game is essentially a standard horizontally scrolling shoot 'em up, it has an innovation that makes it unique in the genre. The player flies a spaceship (specifically, a bioship) which has the standard forward guns to be found in all horizontal scrollers, but it also possesses a weapon that can be manually targeted with a crosshair, in the same manner as in the game Missile Command. This allows the player to fire in any direction with pinpoint accuracy, and adds an extra level of strategy to the game. The game saw an almost arcade perfect port on the Sega Mega Drive. What few changes there were actually enhanced the look of the game such as added parallax scrolling backgrounds in level 2.