Ecco the Dolphin (title screen: Ecco) is an action-adventure game originally developed by Novotrade International for the Mega Drive, and published by Sega in 1992. The game's designer is Ed Annunziata. It is the first installment in the Ecco the Dolphin video game franchise. The player character, Ecco, is a bottlenose dolphin who travels through time to combat hostile extraterrestrials in Earth's oceans and on an alien spacecraft.

Ecco: The Tides of Time is the second game in the Ecco the Dolphin series is the sequel to Ecco the Dolphin for the Sega Mega Drive, Game Gear, and Mega-CD, developed by Novotrade International and released in 1994. The Tides of Time continued the story of the first game and featured similar gameplay with a few new additions.

El Viento (エル・ヴィエント, Eru Viento?, derived from Spanish meaning "The Wind") is a 2D platform video game released by Wolf Team and published by Renovation Products for the Sega Mega Drive/Sega Genesis game console in 1991. It is the second in a trilogy of games, which include Earnest Evans and Anett Futatabi. The game possesses many references to H. P. Lovecraft's esteemed Cthulhu Mythos. As with many Wolf Team games, the music was composed by Motoi Sakuraba.

Elemental Master is a top down shoot 'em up video game developed by Tecno Soft for the Sega Mega Drive and released in 1990 in Japan, and in 1993 in North America by Renovation Products.

Eternal Champions is a fighting game originally conceived by Scott Berfield, produced by Mike Latham for Sega of America, and developed by Sega Interactive Development Division in 1993. It was one of the only fighting games of its time developed from the ground up as a home console title, rather than being released in arcades first and later ported to home systems, as was the standard during that era. Sega released Eternal Champions for their Mega Drive/Genesis in 1993, hoping to capitalize on the fighting game mania that the game industry was in the midst of following the massive success of Street Fighter II (1991) and Mortal Kombat (1992). The game tried to set itself apart with unique features like a heavier emphasis on its story, characters pulled from different time periods, reflectable projectiles, force fields, fighters that carried weapons, a training mode where players had to defend themselves against robotic traps, a novel method of executing moves, and elaborate stage-specific finishing moves called "Overkills". Two years later, the sequel Eternal Champions: Challenge from the Dark Side (sometimes known as Eternal Champions CD or Eternal Champions 2) was released for the Mega-CD/Sega CD. There were also two spin-offs, action/adventure games set in the Eternal Champions universe and featuring some of its characters. Eternal Champions was added to the Wii's Virtual Console download service on December 3, 2007, where it became the first game to be rated 18 by PEGI in the service.