Sally Acorn in Sonic the Hedgehog 2 (aka Sally in Sonic 2) is a fan-made ROM of the game Sonic the Hedgehog 2 for the Sega Mega Drive/Genesis, with Princess Sally Acorn as a playable character in place of Sonic the HedgehogThe game was modified by Sonic Retro member E-122-Psi, with additional programming and coding by other members including MainMemory, Qiuu and Snkenjoi.

Saturday Night Slam Masters, known in Japan as Muscle Bomber – The Body Explosion (Japanese: マッスルボマー ザ・ボディー・エクスプロージョン?), is a 1993 pro wrestling arcade game released for the CP System by Capcom. The game features character designs by manga artist Tetsuo Hara, famous for Fist of the North Star. The game was followed by an updated version titled Muscle Bomber Duo in 1993, and a sequel called Ring of Destruction: Slam Masters II in 1994.

Scooby-Doo Mystery is the name of two video games released by Acclaim in 1995 based on the Scooby-Doo animated series. One of the games was released for the Super Nintendo Entertainment System and is an adventure game with platforming elements. The other title, released for the Sega Mega Drive/Genesis is a more traditional adventure game with a point-and-click-style interface. In both games, players take control of Shaggy Rogers and Scooby-Doo, who help solve various mysteries with other members of Mystery Incorporated who serve minor roles during gameplay.

Sesame Street: Counting Cafe is a Sega Genesis-only game based on the characters of Sesame Street, which is produced by the Children's Television Workshop (now known as Sesame Workshop). Players learn how to count numbers with Grover as he tries to count, climb, and jump while collecting food items for counting. Bert has a tendency to thrown an egg in the mass and alter the order.[15] The skills learned and developed in this game can be used for later childhood, adolescence, and eventually adulthood. North America was the only region in which the game was released; it uses the American English language.

Shadow Blasters (四天明王 Shiten Myouou or Shiten-Myooh) is a platform game developed by Sigma Enterprises for the Sega Genesis video game console in 1990. It was released in Japan and in North America in a localized form.

Shadow of the Beast is a side-scrolling platform computer game produced by Reflections (Later known as Reflections Interactive) and published by Psygnosis in 1989. The original version was released for the Commodore Amiga but the game has been ported to many other systems. The original Amiga release cost £35, an unheard of price for a video game in that era, but it did include a T-shirt in the box bearing a print of the box's artwork. Psygnosis had published numerous side scrollers with high quality graphics prior to the release of Shadow of the Beast (most notably Obliterator). Shadow of the Beast, however, was considered revolutionary because its graphics, with many more colours on screen and up to twelve levels of parallax scrolling backdrops, were of a level rarely if ever seen before in action games. It was also notable for its atmospheric score composed by David Whittaker that used high-quality instrument samples. Shadow of the Beast will be remade on the PlayStation 4.